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KMID : 0665420210360010103
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Korean Journal of Food Culture
2021 Volume.36 No. 1 p.103 ~ p.109
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Anti-inflammatory and Anti-cancer Effects of Agricultural Produce Grown with Organic Germanium-enriched Water
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Lee Myeong-Seon
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Abstract
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The study was conducted to identify the anti-inflammatory and anti-cancer effects in sprouts of mouse-eyed bean(Rhynchosia nulubilis), ginseng (Panax ginseng), perilla (Perilla frutescens), broccoli (Brassica oleracea var. italica), andlettuce (Lactuca sativa) grown with organic germanium concentrate. Western blot analysis was performed to assess the antiinflammatoryactivity of the extract. All extracts exhibited noticeable anti-oxidant activity, indicating a significant correlationbetween the germanium content and anti-oxidant activity (p<0.05). In particular, rat-eyed bean sprouts with the highestgermanium content showed significant anti-inflammatory activity (p<0.05) by significantly inhibiting the expression of theinflammatory complexes, NLRP3, cytokines IL-1β and caspase-1. Ginseng and broccoli sprouts showed strong anti-cancerproperties and had high anti-oxidant effects (p<0.001). Germanium-concentrated water allows the mass production ofagricultural products containing high concentrations of organic germanium. Agricultural produce grown with germaniumconcentrate add organic germanium to various physiological active ingredients, increasing the anti-oxidant and anti-cancereffects. These results strongly suggest that agricultural products containing high germanium concentrations can be used asnovel health supplements to improve health.
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KEYWORD
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Organic germanium, anti-inflammatory, anti-cancer, anti-oxidant, novel health supplements
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